HIV drug resistance surveillance for prioritizing treatment in resource-limited settings
نویسندگان
چکیده
منابع مشابه
HIV drug resistance surveillance for prioritizing treatment in resource-limited settings
Modelling A first-order Monte Carlo state-transmission simulation model of HIV natural history and treatment was applied to resource-limited settings. The model, which had already been published (Yazdanpanah et al. 2005 and Sax et al. 2005, see 'Other Publications of Related Interest' for bibliographic details), was developed for a Cote d'Ivoire setting from the US-based Cost-Effectiveness of P...
متن کاملHIV drug resistance surveillance for prioritizing treatment in resource-limited settings.
BACKGROUND Sentinel testing programs for HIV drug resistance in resource-limited settings can inform policy on antiretroviral therapy (ART) and drug sequencing. OBJECTIVE : To examine the value of resistance surveillance in influencing recommendations toward effective and cost-effective sequencing of ART regimens. METHODS A state-transition model of HIV infection was adapted to simulate cli...
متن کاملAssessments of HIV drug resistance mutations in resource-limited settings.
At the end of 2009, 5.25 million persons were receiving antiretroviral therapy (ART) worldwide, representing an 10fold increase over a period of 5 years [1]. The global scale-up of ART has led to an inevitable increase in HIV drug resistance (HIVDR) and a pool of resistant virus available to establish new infections. The report by Sungkanuparph et al in this issue highlights the need for streng...
متن کاملAn Investigation of Multi-label Classification Techniques for Predicting Hiv Drug Resistance in Resource-limited Settings
South Africa has one of the highest HIV infection rates in the world with more than 5.6 million infected people and consequently has the largest antiretroviral treatment program with more than 1.5 million people on treatment. The development of drug resistance is a major factor impeding the efficacy of antiretroviral treatment. While genotype resistance testing (GRT) is the standard method to d...
متن کاملAn Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
HIV-1 drug resistance has the potential to seriously compromise the effectiveness and impact of antiretroviral therapy (ART). As ART programs in sub-Saharan Africa continue to expand, individuals on ART should be closely monitored for the emergence of drug resistance. Surveillance of transmitted drug resistance to track transmission of viral strains already resistant to ART is also critical. Un...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: AIDS
سال: 2007
ISSN: 0269-9370
DOI: 10.1097/qad.0b013e328011ec53